diff --git a/erpnext/stock/doctype/pick_list/pick_list.py b/erpnext/stock/doctype/pick_list/pick_list.py
index 42ffc9fbb78..91f685304d9 100644
--- a/erpnext/stock/doctype/pick_list/pick_list.py
+++ b/erpnext/stock/doctype/pick_list/pick_list.py
@@ -1468,6 +1468,9 @@ def create_delivery_from_so(pick_list, sales_order_list, target, target_doc=None
 	if not target_doc:
 		return
 
+	if target == "Sales Invoice":
+		target_doc.set("items", [])
+
 	for so in sales_order_list:
 		map_pl_locations(pick_list, item_table_mapper, target_doc, so)