diff --git a/erpnext/stock/doctype/material_request/material_request.py b/erpnext/stock/doctype/material_request/material_request.py
index 8642af2a3dc..050c870e620 100644
--- a/erpnext/stock/doctype/material_request/material_request.py
+++ b/erpnext/stock/doctype/material_request/material_request.py
@@ -10,6 +10,7 @@ import json
 import frappe
 import frappe.defaults
 from frappe import _, msgprint
+from frappe.model.document import Document
 from frappe.model.mapper import get_mapped_doc
 from frappe.query_builder import Order
 from frappe.query_builder.functions import Sum
@@ -766,7 +767,16 @@ def make_purchase_orders_by_supplier(source_name: str, item_suppliers: str | lis
 
 
 @frappe.whitelist()
-def make_request_for_quotation(source_name, target_doc=None):
+def make_request_for_quotation(source_name: str, target_doc: str | dict | Document | None = None):
+	def update_item(obj, target, source_parent):
+		qty = obj.ordered_qty or obj.received_qty
+		target.qty = flt(flt(obj.stock_qty) - flt(qty)) / target.conversion_factor
+		target.stock_qty = target.qty * target.conversion_factor
+
+	def select_item(d):
+		qty = d.ordered_qty or d.received_qty
+		return qty < d.stock_qty
+
 	doclist = get_mapped_doc(
 		"Material Request",
 		source_name,
@@ -782,6 +792,8 @@ def make_request_for_quotation(source_name, target_doc=None):
 					["parent", "material_request"],
 					["project", "project_name"],
 				],
+				"postprocess": update_item,
+				"condition": select_item,
 			},
 		},
 		target_doc,
diff --git a/erpnext/stock/doctype/material_request/test_material_request.py b/erpnext/stock/doctype/material_request/test_material_request.py
index 0dada9746a2..1253f8fcdb0 100644
--- a/erpnext/stock/doctype/material_request/test_material_request.py
+++ b/erpnext/stock/doctype/material_request/test_material_request.py
@@ -14,6 +14,7 @@ from erpnext.stock.doctype.material_request.material_request import (
 	create_pick_list,
 	make_in_transit_stock_entry,
 	make_purchase_order,
+	make_request_for_quotation,
 	make_stock_entry,
 	make_supplier_quotation,
 	raise_work_orders,
@@ -50,6 +51,26 @@ class TestMaterialRequest(ERPNextTestSuite):
 		self.assertEqual(po.doctype, "Purchase Order")
 		self.assertEqual(len(po.get("items")), len(mr.get("items")))
 
+	def test_make_request_for_quotation_skips_ordered_items(self):
+		mr = frappe.copy_doc(self.globalTestRecords["Material Request"][0]).insert()
+		mr = frappe.get_doc("Material Request", mr.name)
+		mr.submit()
+
+		# fully order the first item, leave the second pending
+		po = make_purchase_order(mr.name)
+		po.supplier = "_Test Supplier"
+		po.schedule_date = today()
+		po.items = [po.items[0]]
+		po.items[0].schedule_date = today()
+		po.insert()
+		po.submit()
+
+		rfq = make_request_for_quotation(mr.name)
+
+		self.assertEqual(len(rfq.get("items")), 1)
+		self.assertEqual(rfq.items[0].material_request_item, mr.items[1].name)
+		self.assertEqual(rfq.items[0].qty, mr.items[1].qty)
+
 	def test_make_subcontracted_purchase_order(self):
 		from erpnext.manufacturing.doctype.production_plan.test_production_plan import make_bom
 		from erpnext.stock.doctype.item.test_item import create_item, make_item