diff --git a/erpnext/stock/doctype/stock_entry/stock_entry.py b/erpnext/stock/doctype/stock_entry/stock_entry.py
index 21f3245bbc4..d313c037e02 100644
--- a/erpnext/stock/doctype/stock_entry/stock_entry.py
+++ b/erpnext/stock/doctype/stock_entry/stock_entry.py
@@ -243,6 +243,27 @@ class StockEntry(StockController):
 			self.reset_default_field_value("to_warehouse", "items", "t_warehouse")
 
 		self.validate_same_source_target_warehouse_during_material_transfer()
+		self.validate_raw_materials_exists()
+
+	def validate_raw_materials_exists(self):
+		if self.purpose not in ["Manufacture", "Repack", "Disassemble"]:
+			return
+
+		if frappe.db.get_single_value("Manufacturing Settings", "material_consumption"):
+			return
+
+		raw_materials = []
+		for row in self.items:
+			if row.s_warehouse:
+				raw_materials.append(row.item_code)
+
+		if not raw_materials:
+			frappe.throw(
+				_(
+					"At least one raw material item must be present in the stock entry for the type {0}"
+				).format(bold(self.purpose)),
+				title=_("Raw Materials Missing"),
+			)
 
 	def set_serial_batch_for_disassembly(self):
 		if self.purpose != "Disassemble":
diff --git a/erpnext/stock/doctype/stock_entry/test_stock_entry.py b/erpnext/stock/doctype/stock_entry/test_stock_entry.py
index 0be02756207..2383fabaf89 100644
--- a/erpnext/stock/doctype/stock_entry/test_stock_entry.py
+++ b/erpnext/stock/doctype/stock_entry/test_stock_entry.py
@@ -2232,6 +2232,28 @@ class TestStockEntry(FrappeTestCase):
 		se.save()
 		se.submit()
 
+	def test_raw_material_missing_validation(self):
+		original_value = frappe.db.get_single_value("Manufacturing Settings", "material_consumption")
+		frappe.db.set_single_value("Manufacturing Settings", "material_consumption", 0)
+
+		stock_entry = make_stock_entry(
+			item_code="_Test Item",
+			qty=1,
+			target="_Test Warehouse - _TC",
+			do_not_save=True,
+		)
+
+		stock_entry.purpose = "Manufacture"
+		stock_entry.stock_entry_type = "Manufacture"
+		stock_entry.items[0].is_finished_item = 1
+
+		self.assertRaises(
+			frappe.ValidationError,
+			stock_entry.save,
+		)
+
+		frappe.db.set_single_value("Manufacturing Settings", "material_consumption", original_value)
+
 
 def make_serialized_item(**args):
 	args = frappe._dict(args)