diff --git a/erpnext/stock/doctype/serial_and_batch_bundle/serial_and_batch_bundle.py b/erpnext/stock/doctype/serial_and_batch_bundle/serial_and_batch_bundle.py
index c8558e17474..9cf0ef8e622 100644
--- a/erpnext/stock/doctype/serial_and_batch_bundle/serial_and_batch_bundle.py
+++ b/erpnext/stock/doctype/serial_and_batch_bundle/serial_and_batch_bundle.py
@@ -311,6 +311,30 @@ class SerialandBatchBundle(Document):
 					SerialNoDuplicateError,
 				)
 
+		if (
+			self.voucher_type == "Stock Entry"
+			and self.type_of_transaction == "Inward"
+			and frappe.get_cached_value("Stock Entry", self.voucher_no, "purpose")
+			in ["Manufacture", "Repack"]
+		):
+			serial_nos = frappe.get_all(
+				"Serial No", filters={"name": ("in", serial_nos), "status": "Delivered"}, pluck="name"
+			)
+
+			if serial_nos:
+				if len(serial_nos) == 1:
+					frappe.throw(
+						_(
+							"Serial No {0} is already Delivered. You cannot use them again in Manufacture / Repack entry."
+						).format(bold(serial_nos[0]))
+					)
+				else:
+					frappe.throw(
+						_(
+							"Serial Nos {0} are already Delivered. You cannot use them again in Manufacture / Repack entry."
+						).format(bold(", ".join(serial_nos)))
+					)
+
 	def throw_error_message(self, message, exception=frappe.ValidationError):
 		frappe.throw(_(message), exception, title=_("Error"))
 
diff --git a/erpnext/stock/doctype/stock_entry/test_stock_entry.py b/erpnext/stock/doctype/stock_entry/test_stock_entry.py
index d0143941660..98205a7d8f3 100644
--- a/erpnext/stock/doctype/stock_entry/test_stock_entry.py
+++ b/erpnext/stock/doctype/stock_entry/test_stock_entry.py
@@ -2147,6 +2147,45 @@ class TestStockEntry(IntegrationTestCase):
 
 		self.assertEqual(incoming_rate, 125.0)
 
+	def test_prevent_reuse_delivered_serial_no_in_repack(self):
+		from erpnext.stock.doctype.delivery_note.test_delivery_note import create_delivery_note
+
+		item = "Test Prevent Reuse Delivered Serial No"
+		warehouse = "_Test Warehouse - _TC"
+
+		item_doc = make_item(item, {"is_stock_item": 1, "has_serial_no": 1, "serial_no_series": "SHGJ.####"})
+
+		make_stock_entry(item_code="_Test Item", target=warehouse, qty=2, rate=100)
+		make_stock_entry(item_code=item, target=warehouse, qty=2, rate=100)
+
+		dn = create_delivery_note(item_code=item, qty=2)
+		delivered_serial_no = get_serial_nos_from_bundle(dn.get("items")[0].serial_and_batch_bundle)[0]
+
+		se = make_stock_entry(
+			item_code="_Test Item", source=warehouse, qty=1, purpose="Repack", do_not_save=True
+		)
+		se.append(
+			"items",
+			{
+				"item_code": item_doc.name,
+				"item_name": item_doc.item_name,
+				"s_warehouse": None,
+				"t_warehouse": warehouse,
+				"description": item_doc.description,
+				"uom": item_doc.stock_uom,
+				"qty": 1,
+				"use_serial_batch_fields": 1,
+				"serial_no": delivered_serial_no,
+			},
+		)
+
+		se.save()
+		status = frappe.db.get_value("Serial No", delivered_serial_no, "status")
+
+		self.assertEqual(status, "Delivered")
+		self.assertEqual(se.purpose, "Repack")
+		self.assertRaises(frappe.ValidationError, se.submit)
+
 
 def make_serialized_item(self, **args):
 	args = frappe._dict(args)
diff --git a/erpnext/stock/serial_batch_bundle.py b/erpnext/stock/serial_batch_bundle.py
index ca40f00df6e..732faefe38f 100644
--- a/erpnext/stock/serial_batch_bundle.py
+++ b/erpnext/stock/serial_batch_bundle.py
@@ -419,12 +419,7 @@ class SerialBatchBundle:
 
 		self.update_serial_no_status_warehouse(self.sle, serial_nos)
 
-	def update_serial_no_status_warehouse(self, sle, serial_nos):
-		warehouse = sle.warehouse if sle.actual_qty > 0 else None
-
-		if isinstance(serial_nos, str):
-			serial_nos = [serial_nos]
-
+	def get_status_for_serial_nos(self, sle):
 		status = "Inactive"
 		if sle.actual_qty < 0:
 			status = "Delivered"
@@ -438,6 +433,23 @@ class SerialBatchBundle:
 				]:
 					status = "Consumed"
 
+			if sle.is_cancelled == 1 and (
+				sle.voucher_type in ["Purchase Invoice", "Purchase Receipt"] or status == "Consumed"
+			):
+				status = "Inactive"
+
+		return status
+
+	def update_serial_no_status_warehouse(self, sle, serial_nos):
+		warehouse = sle.warehouse if sle.actual_qty > 0 else None
+
+		if isinstance(serial_nos, str):
+			serial_nos = [serial_nos]
+
+		status = "Active"
+		if not warehouse:
+			status = self.get_status_for_serial_nos(sle)
+
 		customer = None
 		if sle.voucher_type in ["Sales Invoice", "Delivery Note"] and sle.actual_qty < 0:
 			customer = frappe.get_cached_value(sle.voucher_type, sle.voucher_no, "customer")