diff --git a/erpnext/buying/doctype/request_for_quotation/request_for_quotation.py b/erpnext/buying/doctype/request_for_quotation/request_for_quotation.py
index 0805dff2ad4..37d9fb06ea2 100644
--- a/erpnext/buying/doctype/request_for_quotation/request_for_quotation.py
+++ b/erpnext/buying/doctype/request_for_quotation/request_for_quotation.py
@@ -9,6 +9,7 @@ from frappe import _
 from frappe.contacts.doctype.contact.contact import get_full_name
 from frappe.core.doctype.communication.email import make
 from frappe.desk.form.load import get_attachments
+from frappe.model.document import Document
 from frappe.model.mapper import get_mapped_doc
 from frappe.query_builder import Order
 from frappe.utils import get_url
@@ -489,36 +490,73 @@ def make_supplier_quotation_from_rfq(source_name, target_doc=None, for_supplier=
 
 # This method is used to make supplier quotation from supplier's portal.
 @frappe.whitelist()
-def create_supplier_quotation(doc):
+def create_supplier_quotation(doc: str | Document | dict):
 	if isinstance(doc, str):
 		doc = json.loads(doc)
+	supplier = doc.get("supplier")
 
-	if frappe.session.user not in frappe.get_all(
-		"Portal User", {"parent": doc.get("supplier")}, pluck="user"
-	):
+	if frappe.session.user not in frappe.get_all("Portal User", {"parent": supplier}, pluck="user"):
 		frappe.throw(_("Not Permitted"), frappe.PermissionError)
 
-	try:
-		sq_doc = frappe.get_doc(
-			{
-				"doctype": "Supplier Quotation",
-				"supplier": doc.get("supplier"),
-				"terms": doc.get("terms"),
-				"company": doc.get("company"),
-				"currency": doc.get("currency")
-				or get_party_account_currency("Supplier", doc.get("supplier"), doc.get("company")),
-				"buying_price_list": doc.get("buying_price_list")
-				or frappe.db.get_single_value("Buying Settings", "buying_price_list"),
-			}
+	validate_existing_supplier_quotation(supplier, doc.get("items"))
+
+	sq_doc = frappe.get_doc(
+		{
+			"doctype": "Supplier Quotation",
+			"supplier": supplier,
+			"terms": doc.get("terms"),
+			"company": doc.get("company"),
+			"currency": doc.get("currency")
+			or get_party_account_currency("Supplier", supplier, doc.get("company")),
+			"buying_price_list": doc.get("buying_price_list")
+			or frappe.db.get_single_value("Buying Settings", "buying_price_list"),
+		}
+	)
+	add_items(sq_doc, supplier, doc.get("items"))
+	sq_doc.flags.ignore_permissions = True
+	sq_doc.run_method("set_missing_values")
+	sq_doc.save()
+	frappe.msgprint(_("Supplier Quotation {0} Created").format(sq_doc.name))
+	return sq_doc.name
+
+
+def validate_existing_supplier_quotation(supplier, items):
+	request_for_quotations = {item.get("parent") for item in items if item.get("parent")}
+	if not request_for_quotations:
+		return
+
+	rfq = frappe.qb.DocType("Request for Quotation")
+	(
+		frappe.qb.from_(rfq)
+		.select(rfq.name)
+		.where(rfq.name.isin(request_for_quotations))
+		.orderby(rfq.name)
+		.for_update()
+	).run()
+
+	sq = frappe.qb.DocType("Supplier Quotation")
+	sqi = frappe.qb.DocType("Supplier Quotation Item")
+	existing_quotation = (
+		frappe.qb.from_(sq)
+		.inner_join(sqi)
+		.on(sq.name == sqi.parent)
+		.select(sq.name, sqi.request_for_quotation)
+		.where(
+			(sq.docstatus < 2)
+			& (sq.supplier == supplier)
+			& (sqi.request_for_quotation.isin(request_for_quotations))
+		)
+		.limit(1)
+	).run(as_dict=True)
+
+	if existing_quotation:
+		existing_quotation = existing_quotation[0]
+		frappe.throw(
+			_("Supplier Quotation {0} already exists against Request for Quotation {1}").format(
+				frappe.bold(existing_quotation.name),
+				frappe.bold(existing_quotation.request_for_quotation),
+			)
 		)
-		add_items(sq_doc, doc.get("supplier"), doc.get("items"))
-		sq_doc.flags.ignore_permissions = True
-		sq_doc.run_method("set_missing_values")
-		sq_doc.save()
-		frappe.msgprint(_("Supplier Quotation {0} Created").format(sq_doc.name))
-		return sq_doc.name
-	except Exception:
-		return None
 
 
 def add_items(sq_doc, supplier, items):
diff --git a/erpnext/templates/pages/rfq.html b/erpnext/templates/pages/rfq.html
index 8d55d6b47e1..d2a9382dc6b 100644
--- a/erpnext/templates/pages/rfq.html
+++ b/erpnext/templates/pages/rfq.html
@@ -13,7 +13,7 @@
 {% endblock %}
 
 {% block header_actions %}
-{% if doc.items %}
+{% if doc.items and not doc.rfq_links %}
 <button class="btn btn-primary btn-sm"
     type="button">
     {{ _("Make Quotation") }}</button>